Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | AGXT | P21549 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6215110 | 0.84 | IDO1 (0.47) | IDO1CYP2D6TAAR1PPARGPPARA | |
| SCHEMBL2400378 | 0.81 | IDO1 (0.47) | TSHREPHX1IDO1TAAR1SLC6A2 | |
| SCHEMBL455196 | 0.81 | TSHR (0.44) | TSHRIDO1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8200897 | 0.81 | TAAR1 (0.43) | EPHX1CYP2D6TAAR1SLC6A2SLC6A4 | |
| SCHEMBL8784163 | 0.79 | EPHX1 (0.48) | TSHREPHX1CYP1A2CYP2D6TAAR1 | |
| SCHEMBL3276722 | 0.79 | TSHR (0.52) | TSHREPHX1IDO1SLC1A3SLC1A2 | |
| SCHEMBL28631602 | 0.79 | TSHR (0.52) | TSHRIDO1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL1357788 | 0.78 | SLC1A3 (0.50) | TSHREPHX1IDO1SLC1A3SLC1A2 | |
| SCHEMBL3359525 | 0.78 | TSHR (0.41) | TSHRIDO1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7332513 | 0.76 | CYP2D6 (0.50) | TSHRCYP2D6TAAR1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101812144-B | late transition metal olefin polymerization catalyst and preparation method thereof | PETROCHINA CO LTD | 2012-03-07 | — | — | CN | disclosed |
| US-20120045840-A1 | CHROMOPHORE AND POLYMER CAPABLE OF DETECTING THE PRESENCE OF VARIOUS NEUROTOXINS AND METHOD OF USE | NDSU-RESEARCH FOUNDATION (US) | 2012-02-23 | — | — | US | disclosed |
| US-7910058-B2 | Chromophore and polymer capable of detecting the presence of various neurotoxins and method of use | NDSU—Research Foundation (US) | 2011-03-22 | — | — | US | disclosed |
| US-7897402-B2 | Chromophore and polymer capable of detecting the presence of various neurotoxins and method of use | NDSU-RESEARCH FOUNDATION (US) | 2011-03-01 | — | — | US | disclosed |
| US-20110028721-A1 | Chromophore and Polymer Capable of Detecting the Presence of Various Neurotoxins and Method of Use | NDSU-RESEARCH FOUNDATION (US) | 2011-02-03 | — | — | US | disclosed |
| US-20110027896-A1 | CHROMOPHORE AND POLYMER CAPABLE OF DETECTING THE PRESENCE OF VARIOUS NEUROTOXINS AND METHOD OF USE | NDSU-RESEARCH FOUNDATION (US) | 2011-02-03 | — | — | US | disclosed |
| CN-101812144-A | Late transition metal olefin polymerization catalyst and preparation method thereof | PETROCHINA CO LTD | 2010-08-25 | — | — | CN | disclosed |
| US-7700040-B2 | Neurotoxin sensor based on chromophoric polymers | NDSU-RESEARCH FOUNDATION (US) | 2010-04-20 | — | — | US | disclosed |
| US-20080138912-A1 | Chromophore and polymer capable of detecting the presence of various neurotoxins and method of use | NORTH DAKOTA STATE UNIVERSITY (US) | 2008-06-12 | — | — | US | disclosed |
| WO-2006081345-A1 | CHROMOPHORE AND POLYMER CAPABLE OF DETECTING THE PRESENCE OF VARIOUS NEUROTOXINS AND METHOD OF USE | NORTH DAKOTA STATE UNIVERSITY (US) | 2006-08-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028721-A1 | Chromophore and Polymer Capable of Detecting the Presence of Various Neurotoxins and Method of Use | DDT, MB, CACYBP | TSHR 1143/4885EPHX1 2131/4885IDO1 3099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.