SCHEMBL3276722

SCHEMBL3276722

c1ccc(COC(Cc2ccccc2)OCc2ccccc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.52
EPHX1 P07099 1/20 0.48
IDO1 P14902 1/20 0.48
AGXT P21549 1/20 0.46
SLC1A3 P43003 2/20 0.46
SLC1A2 P43004 2/20 0.46
SLC1A1 P43005 2/20 0.46
CYP1A2 P05177 2/20 0.46
MEN1 O00255 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
KMT2A Q03164 1/20 0.46
TAAR1 Q96RJ0 4/20 0.44
SLC6A2 P23975 3/20 0.44
SLC6A4 P31645 2/20 0.44
SLC6A3 Q01959 2/20 0.44
SIGMAR1 Q99720 2/20 0.44
MAOA P21397 1/20 0.44
CYP2A6 P11509 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8333715 0.88 TSHR (0.41) TSHREPHX1IDO1AGXTSLC1A3
SCHEMBL4299693 0.81 IDO1 (0.50) TSHREPHX1IDO1AGXTSLC1A3
SCHEMBL17863583 0.81 TSHR (0.48) TSHREPHX1IDO1AGXTSLC1A3
SCHEMBL2644671 0.81 TSHR (0.48) TSHRIDO1AGXTSLC1A3SLC1A2
SCHEMBL2554445 0.81 TAAR1 (0.52) TSHREPHX1IDO1SLC1A3SLC1A2
SCHEMBL7011964 0.81 TSHR (0.48) TSHRIDO1AGXTSLC1A3SLC1A2
SCHEMBL2644673 0.81 TSHR (0.48) TSHRIDO1AGXTSLC1A3SLC1A2
SCHEMBL31697649 0.81 TSHR (0.48) TSHRIDO1AGXTSLC1A3SLC1A2
SCHEMBL11687119 0.81 TSHR (0.48) TSHRIDO1AGXTSLC1A3SLC1A2
SCHEMBL3079998 0.81 TSHR (0.48) TSHRIDO1AGXTSLC1A3SLC1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030036489-A1 Consumable composition comprising perfumed particles and article containing the same THE PROCTER & GAMBLE COMPANY 2003-02-20 US claimed
WO-2002090479-A1 PERFUMED PARTICLES AND ARTICLES CONTAINING THE SAME THE PROCTER & GAMBLE COMPANY (US) 2002-11-14 WO claimed
WO-2002090481-A1 COMPOSITIONS AND ARTICLES FOR EFFECTIVE DEPOSITION OF PERFUME THE PROCTER & GAMBLE COMPANY (US) 2002-11-14 WO claimed
EP-2741731-B1 ENCAPSULATES PROCTER & GAMBLE (US) 2017-05-17 EP disclosed
US-8889614-B2 Encapsulates THE PROCTER & GAMBLE COMPANY (US) 2014-11-18 US disclosed
US-8539631-B2 Roller for providing benefits to fabric THE PROCTER & GAMBLE COMPANY (US) 2013-09-24 US disclosed
EP-2468239-B1 Encapsulates PROCTER & GAMBLE INTERNAT OPERATIONS SA (CH) 2013-09-18 EP disclosed
EP-2468239-A1 Encapsulates Procter & Gamble International Operations SA (CH) 2012-06-27 EP disclosed
US-20120152268-A1 ENCAPSULATES PROCTER & GAMBLE COMPANY, THE 2012-06-21 US disclosed
EP-1920042-B1 PARTICLES CONTAINING PERFUME HAVING IMPROVED FRAGRANCED PROPERTIES HENKEL AG & CO KGAA (DE) 2010-06-23 EP disclosed
EP-2046929-A1 LIQUID SUPPORT Henkel AG & Co. KGaA (DE) 2009-04-15 EP disclosed
EP-1383547-A2 AIR FRESHENING COMPOSITIONS, ARTICLES COMPRISING SAME AND METHODS FOR PREPARING SAME THE PROCTER & GAMBLE COMPANY (US) 2004-01-28 EP disclosed
EP-1383858-A1 DRYER-ADDED FABRIC SOFTENING ARTICLES AND METHODS The Procter & Gamble Company (US) 2004-01-28 EP disclosed
US-20030036489-A1 Consumable composition comprising perfumed particles and article containing the same THE PROCTER & GAMBLE COMPANY 2003-02-20 US disclosed
US-20030024997-A1 Air freshening compositions, articles comprising same and methods THE PROCTER & GAMBLE COMPANY 2003-02-06 US disclosed
US-20030013632-A1 Dryer-added fabric softening articles and methods THE PROCTER & GAMBLE COMPANY 2003-01-16 US disclosed
WO-2002090480-A1 DRYER-ADDED FABRIC SOFTENING ARTICLES AND METHODS THE PROCTER & GAMBLE COMPANY (US) 2002-11-14 WO disclosed
WO-2002089862-A2 AIR FRESHENING COMPOSITIONS, ARTICLES COMPRISING SAME AND METHODS FOR PREPARING SAME THE PROCTER & GAMBLE COMPANY (US) 2002-11-14 WO disclosed
WO-2002090479-A1 PERFUMED PARTICLES AND ARTICLES CONTAINING THE SAME THE PROCTER & GAMBLE COMPANY (US) 2002-11-14 WO disclosed
WO-2002090481-A1 COMPOSITIONS AND ARTICLES FOR EFFECTIVE DEPOSITION OF PERFUME THE PROCTER & GAMBLE COMPANY (US) 2002-11-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030024997-A1 Air freshening compositions, articles comprising same and methods PIEZO1, TMEM63A, KIT TSHR 4670/4885EPHX1 4029/4885IDO1 2894/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.