SCHEMBL6599221

SCHEMBL6599221

Nn1cnc2ccc[c]c21

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7814440 0.76 TDP1 (0.34) TDP1
SCHEMBL7818229 0.72 TDP1 (0.39) TDP1
SCHEMBL29072351 0.72 HTT (0.55)
SCHEMBL7811036 0.68 CYP11B1 (0.58) TDP1
SCHEMBL29544857 0.66 TDP1 (0.54) TDP1
SCHEMBL145442 0.66 TDP1 (0.54) TDP1
Hydrochloric Acid SCHEMBL11255423 0.64 TDP1 (0.52) TDP1
SCHEMBL5317523 0.63 TP53 (0.41)
SCHEMBL6599150 0.60 TDP1 (0.31) TDP1
SCHEMBL16573409 0.60 DPP4 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1385833-A1 TRIAZINYL AMIDE DERIVATIVES AS ANGIOGENESIS INHIBITORS Amgen Inc. (US) 2004-02-04 EP disclosed
WO-2002083654-A1 TRIAZINYL AMIDE DERIVATIVES AS ANGIOGENESIS INHIBITORS AMGEN INC. (US) 2002-10-24 WO disclosed