SCHEMBL145442

SCHEMBL145442

Nn1cnc2ccccc21

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.54
HTT P42858 2/20 0.52
POLB P06746 1/20 0.47
TNF P01375 1/20 0.47
CYP11B1 P15538 1/20 0.47
CYP11B2 P19099 1/20 0.47
FGFR1 P11362 1/20 0.46
ALDH1A1 P00352 1/20 0.45
CYP1A2 P05177 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2D6 P10635 1/20 0.45
MAPT P10636 1/20 0.45
CYP2C9 P11712 1/20 0.45
THPO P40225 1/20 0.45
CYP4Z1 Q86W10 1/20 0.45
ROCK1 Q13464 1/20 0.44
MKNK1 Q9BUB5 1/20 0.44
MKNK2 Q9HBH9 1/20 0.44
LMNA P02545 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29544857 1.00 TDP1 (0.54) TDP1HTTPOLBTNFCYP11B1
Hydrochloric Acid SCHEMBL11255423 0.98 TDP1 (0.52) TDP1HTTPOLBTNFCYP11B1
Pyridine SCHEMBL29278732 0.88 POLB (0.47) TDP1HTTPOLBTNFCYP11B1
Quinoline SCHEMBL925691 0.85 ALDH1A1 (0.59) TDP1HTTPOLBTNFCYP11B1
SCHEMBL22298467 0.78 FGFR1 (0.54) HTTTNFCYP11B1CYP11B2FGFR1
SCHEMBL7196401 0.75 TDP1 (0.58) TDP1HTTPOLBTNFCYP11B1
SCHEMBL2489876 0.73 TDP1 (0.56) TDP1HTTPOLBTNFCYP11B1
Methylamine SCHEMBL28557648 0.73 TDP1 (0.55) TDP1HTTPOLBTNFCYP11B1
SCHEMBL8668369 0.71 TDP1 (0.54) TDP1HTTPOLBTNFCYP11B1
SCHEMBL9062626 0.71 TDP1 (0.54) TDP1HTTPOLBTNFCYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3152 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12630744-B2 Polishing compositions and methods of use thereof FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2026-05-19 US claimed
US-20260042976-A1 COMPOSITIONS AND METHODS OF USE THEREOF FUJIFILM ELECTRONIC MAT USA INC (US) 2026-02-12 US claimed
EP-4688987-A1 POLISHING COMPOSITIONS AND METHODS OF USE THEREOF FUJIFILM Electronic Materials U.S.A, Inc. (US) 2026-02-11 EP claimed
EP-4689020-A1 FUEL ADDITIVE COMPOSITIONS AND METHODS FOR CONTROLLING DEPOSITS Chevron U.S.A. Inc. (US) 2026-02-11 EP claimed
EP-4653506-A1 CHEMICAL MECHANICAL POLISHING COMPOSITIONS AND METHODS OF USE THEREOF FUJIFILM Electronic Materials U.S.A, Inc. (US) 2025-11-26 EP claimed
US-12463229-B2 Bipolar ionomer membrane CAMX POWER LLC (US) 2025-11-04 US claimed
US-20250333622-A1 POLISHING COMPOSITIONS AND METHODS OF USE THEREOF FUJIFILM ELECTRONIC MAT USA INC (US) 2025-10-30 US claimed
EP-4626996-A1 POLISHING COMPOSITIONS AND METHODS OF USE THEREOF FUJIFILM Electronic Materials U.S.A, Inc. (US) 2025-10-08 EP claimed
US-12398291-B2 Polishing compositions and methods of use thereof FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2025-08-26 US claimed
EP-3411430-B1 BIPOLAR IONOMER MEMBRANE CAMX POWER L L C (US) 2025-08-13 EP claimed
EP-0582789-A1 Novel 7-(substituted)-8-(substituted)-9- (substituted glycyl)amido -6-demethyl-6-deoxytetracyclines AMERICAN CYANAMID COMPANY (US) 1994-02-16 EP claimed
US-5243033-A Dyeing or printing of cellulose CIBA-GEIGY CORPORATION (US) 1993-09-07 US claimed
US-5232462-A Lightfast, colorfast CIBA-GEIGY CORPORATION (US) 1993-08-03 US claimed
EP-0324988-B1 4-CHLOR-3-SULFAMOYL BENZOIC ACID HYDRAZIDES, PROCESS FOR THEIR PREPARATION, MEDICINES CONTAINING THEM AND USE OF THESE COMPOUNDS IN THE PREPARATION OF DIURETIC AND SALT REDUCING ACTIVITY MEDICINES CHINOIN GYOGYSZER ES VEGYESZET (HU) 1992-04-29 EP claimed
WO-1992000981-A1 NOVEL 3-SUBSTITUTED CEPHEM COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF DAE WOONG PHARMACEUTICAL CO., LTD. (KR) 1992-01-23 WO claimed
US-5017471-A Reagent for peroxidase detection EPITOPE, INC. (US) 1991-05-21 US claimed
EP-0343708-A2 Avermectin derivatives MERCK & CO. INC. (US) 1989-11-29 EP claimed
US-4873224-A Avermectin derivatives MERCK & CO., INC. (US) 1989-10-10 US claimed
EP-0324988-A1 4-Chlor-3-sulfamoyl benzoic acid hydrazides, process for their preparation, medicines containing them and use of these compounds in the preparation of diuretic and salt reducing activity medicines CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) 1989-07-26 EP claimed
US-4841049-A FOR CELLULOSIC FIBERS; BRIGHT BLUE COLORS; WET- AND LIGHTFAST CIBA-GEIGY CORPORATION (US) 1989-06-20 US claimed