SCHEMBL6599362

SCHEMBL6599362

CCOC(=O)c1ccc(-c2noc([C@H](CCCC3CCCCC3)CC(=O)OC(C)(C)C)n2)cn1

nearest known ligand 0.63

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BMP1 P13497 20/20 0.63
MMP2 P08253 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6595914 0.90 BMP1 (0.69) BMP1MMP2
SCHEMBL6600069 0.90 BMP1 (0.77) BMP1MMP2
SCHEMBL6598425 0.88 BMP1 (0.81) BMP1MMP2
SCHEMBL6598160 0.85 BMP1 (0.62) BMP1MMP2
SCHEMBL6601771 0.85 BMP1 (0.79) BMP1MMP2
SCHEMBL6600899 0.83 BMP1 (0.62) BMP1MMP2
SCHEMBL5406890 0.81 BMP1 (0.75) BMP1MMP2
SCHEMBL6877169 0.81 BMP1 (0.54) BMP1
SCHEMBL5408426 0.80 BMP1 (0.55) BMP1MMP2
SCHEMBL6597336 0.79 BMP1 (0.82) BMP1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1373264-B1 3-HETEROCYCLYLPROPANOHYDROXAMIC ACID AS PROCOLLAGEN C-PROTEINASE INHIBITORS PFIZER LTD (GB) 2004-12-22 EP disclosed
EP-1373264-A1 3-HETEROCYCLYLPROPANOHYDROXAMIC ACID AS PROCOLLAGEN C-PROTEINASE INHIBITORS Pfizer Limited (GB) 2004-01-02 EP disclosed
WO-2002079200-A1 3-HETEROCYCLYLPROPANOHYDROXAMIC ACID AS PROCOLLAGEN C-PROTEINASE INHIBITORS PFIZER LIMITED (GB) 2002-10-10 WO disclosed