Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MPI | P34949 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27303996 | 0.81 | HSD17B10 (0.53) | KDM4EALDH1A1HPGDTDP1GAA | |
| SCHEMBL10553981 | 0.80 | KDM4E (0.50) | KDM4EALDH1A1HPGDTDP1GAA | |
| SCHEMBL11771726 | 0.80 | KDM4E (0.50) | KDM4EALDH1A1HPGDTDP1GAA | |
| SCHEMBL20390576 | 0.79 | NISCH (0.46) | KDM4EALDH1A1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL15293725 | 0.79 | KDM4E (0.49) | KDM4EALDH1A1HPGDTDP1GAA | |
| SCHEMBL10697621 | 0.78 | KDM4E (0.59) | KDM4EALDH1A1HPGDTDP1GAA | |
| Hydrochloric Acid SCHEMBL10555133 | 0.77 | KDM4E (0.47) | KDM4EALDH1A1HPGDTDP1GAA | |
| SCHEMBL10552598 | 0.77 | PARP1 (0.51) | KDM4EALDH1A1HPGDTDP1GAA | |
| SCHEMBL10556612 | 0.76 | KDM4E (0.46) | KDM4EALDH1A1HPGDTDP1GAA | |
| SCHEMBL10559417 | 0.76 | KDM4E (0.48) | KDM4EALDH1A1HPGDTDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1417178-A2 | HETEROCYCLIC AMIDE DERIVATIVES AND THE USE THEREOF AS PESTICIDES | Bayer CropScience AG (DE) | 2004-05-12 | — | — | EP | claimed |
| WO-2003004464-A2 | HETEROCYCLIC AMIDE DERIVATIVES AND THE USE THEREOF AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2003-01-16 | — | — | WO | claimed |
| EP-1417178-A2 | HETEROCYCLIC AMIDE DERIVATIVES AND THE USE THEREOF AS PESTICIDES | Bayer CropScience AG (DE) | 2004-05-12 | — | — | EP | disclosed |
| WO-2003004464-A2 | HETEROCYCLIC AMIDE DERIVATIVES AND THE USE THEREOF AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2003-01-16 | — | — | WO | disclosed |
| EP-0253084-A2 | 1,3-Disubstituted imidazolium salts | F. HOFFMANN-LA ROCHE AG (CH) | 1988-01-20 | — | — | EP | disclosed |