Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MPI | P34949 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | KIT | P10721 | 5/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30387478 | 0.83 | KDM4E (0.55) | KDM4EHSD17B10ALDH1A1GAAMPI | |
| SCHEMBL26093677 | 0.83 | KDM4E (0.55) | KDM4EHSD17B10ALDH1A1GAAMPI | |
| SCHEMBL6599439 | 0.78 | KDM4E (0.56) | KDM4EALDH1A1GAAMPIGFER | |
| SCHEMBL11780539 | 0.77 | HPGD (0.52) | KDM4EHSD17B10ALDH1A1GAAMPI | |
| SCHEMBL15330739 | 0.77 | KDM4E (0.49) | KDM4EHSD17B10ALDH1A1GAAMPI | |
| SCHEMBL29008478 | 0.76 | KDM4E (0.48) | KDM4EHSD17B10ALDH1A1GAAMPI | |
| SCHEMBL1660430 | 0.75 | KDM4E (0.60) | KDM4EHSD17B10ALDH1A1KITPDGFRB | |
| SCHEMBL7708794 | 0.74 | KDM4E (0.54) | KDM4EHSD17B10ALDH1A1GAAMPI | |
| SCHEMBL14381414 | 0.73 | ALDH1A1 (0.51) | KDM4EHSD17B10ALDH1A1GAAMPI | |
| SCHEMBL7370877 | 0.73 | MEN1 (0.48) | KDM4EHSD17B10ALDH1A1GAAMPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253084-A2 | 1,3-Disubstituted imidazolium salts | F. HOFFMANN-LA ROCHE AG (CH) | 1988-01-20 | — | — | EP | disclosed |