Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 15/20 | 0.67 |
| ▸ | HTR1D | P28221 | 2/20 | 0.67 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6598221 | 0.91 | HTR1A (0.62) | HTR1AHTR1DADRA1ADRD2 | |
| SCHEMBL6598541 | 0.87 | HTR1A (0.65) | HTR1AHTR1D | |
| SCHEMBL6618280 | 0.85 | HTR1A (0.71) | HTR1AHTR1D | |
| SCHEMBL29708061 | 0.80 | HTR1A (1.00) | HTR1AHTR1D | |
| SCHEMBL6597327 | 0.80 | HTR1A (1.00) | HTR1AHTR1D | |
| SCHEMBL6600330 | 0.80 | HTR1A (0.70) | HTR1AHTR1DDRD2DRD3 | |
| SCHEMBL6598764 | 0.79 | HTR1A (1.00) | HTR1AHTR1DDRD2DRD3 | |
| SCHEMBL1578260 | 0.78 | HTR1A (1.00) | HTR1AHTR1DDRD2 | |
| SCHEMBL7722436 | 0.77 | HTR1A (0.84) | HTR1AHTR1DDRD2DRD3 | |
| SCHEMBL6599023 | 0.77 | HTR1A (1.00) | HTR1AHTR1DDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1008594-B1 | COMPOUNDS DERIVED FROM THOPHENE AND BENZOTHIOPHENE, AND RELATED UTILISATION AND COMPOSITION | VITA LAB (ES) | 2004-03-17 | — | — | EP | disclosed |
| US-6262056-B1 | TREATING ANXIETY OR DEPRESSION | VITA-INVEST, SA (ES) | 2001-07-17 | — | — | US | disclosed |
| EP-1008594-A1 | COMPOUNDS DERIVED FROM THOPHENE AND BENZOTHIOPHENE, AND RELATED UTILISATION AND COMPOSITION | VITA-INVEST, S.A. (ES) | 2000-06-14 | — | — | EP | disclosed |