Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 10/20 | 0.42 |
| ▸ | FNTB | P49356 | 10/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.37 |
| ▸ | NLN | Q9BYT8 | 1/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6605799 | 0.93 | FNTA (0.38) | FNTAFNTBCYP19A1ADRA2AADRA2B | |
| SCHEMBL6599586 | 0.93 | CYP19A1 (0.42) | FNTAFNTBCYP19A1ADRA2AADRA2B | |
| SCHEMBL6608403 | 0.93 | FNTA (0.45) | FNTAFNTBCYP19A1ADRA2AADRA2B | |
| SCHEMBL6599678 | 0.93 | FNTA (0.40) | FNTAFNTBADRA2AADRA2BADRA2C | |
| SCHEMBL6609122 | 0.91 | FNTA (0.44) | FNTAFNTBADRA2AADRA2BADRA2C | |
| SCHEMBL6598795 | 0.91 | FNTA (0.38) | FNTAFNTBADRA2AADRA2BADRA2C | |
| SCHEMBL6602760 | 0.89 | FNTA (0.37) | FNTAFNTBADRA2AADRA2BADRA2C | |
| SCHEMBL6610935 | 0.87 | ADRA2A (0.39) | FNTAFNTBADRA2AADRA2BADRA2C | |
| Toluene SCHEMBL27468825 | 0.84 | FNTA (0.43) | FNTAFNTBADRA2AADRA2BADRA2C | |
| SCHEMBL6607577 | 0.84 | FNTA (0.37) | FNTAFNTBADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1169320-B1 | FARNESYL TRANSFERASE INHIBITORS HAVING A PYRROLE STRUCTURE AND PROCESS FOR PREPARATION THEREOF | LG CHEM INVESTMENT LTD (KR) | 2004-09-22 | — | — | EP | claimed |