Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 11/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 6/20 | 0.39 |
| ▸ | NOS2 | P35228 | 3/20 | 0.38 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5387482 | 0.89 | NOS1 (0.58) | NOS1ADRA1DADRA1AADRA1BNOS3 | |
| SCHEMBL5387479 | 0.89 | NOS1 (0.58) | NOS1ADRA1DADRA1AADRA1BNOS3 | |
| SCHEMBL6599626 | 0.87 | NOS1 (0.61) | NOS1ADRA1DADRA1AADRA1BNOS3 | |
| SCHEMBL6599622 | 0.87 | NOS1 (0.61) | NOS1ADRA1DADRA1AADRA1BNOS3 | |
| SCHEMBL5382722 | 0.86 | NOS1 (0.56) | NOS1ADRA1DADRA1AADRA1BNOS3 | |
| SCHEMBL5382719 | 0.86 | NOS1 (0.56) | NOS1ADRA1DADRA1AADRA1BNOS3 | |
| SCHEMBL5389928 | 0.82 | NOS1 (0.67) | NOS1ADRA1DADRA1AADRA1B | |
| SCHEMBL5389933 | 0.82 | NOS1 (0.67) | NOS1ADRA1DADRA1AADRA1B | |
| SCHEMBL5391587 | 0.81 | NOS1 (0.59) | NOS1ADRA1DADRA1AADRA1BNOS2 | |
| SCHEMBL5391592 | 0.81 | NOS1 (0.59) | NOS1ADRA1DADRA1AADRA1BNOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1265891-B1 | NOVEL LIPOIC ACID HETEROCYCLIC OR BENZENE DERIVATIVES, PREPARATION AND USE THEREOF AS MEDICINES | CONSEILS DE RECH SET D APPLIC (FR) | 2004-12-29 | — | — | EP | claimed |