SCHEMBL6599670

SCHEMBL6599670

O=C(C[C@@H](CCCC1CCCCC1)c1nc(-c2ccc(N3CC(N4CCOCC4)C3)nc2)no1)NO

nearest known ligand 0.69

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
BMP1 P13497 20/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6597711 0.92 BMP1 (0.58) BMP1
SCHEMBL6601594 0.90 BMP1 (0.76) BMP1
SCHEMBL6601950 0.87 BMP1 (0.74) BMP1
SCHEMBL6601485 0.87 BMP1 (0.72) BMP1
SCHEMBL6600876 0.87 BMP1 (0.72) BMP1
SCHEMBL6601428 0.87 BMP1 (0.75) BMP1
SCHEMBL6599806 0.87 BMP1 (0.72) BMP1
SCHEMBL6599850 0.86 BMP1 (0.71) BMP1
SCHEMBL6599739 0.82 BMP1 (1.00) BMP1
SCHEMBL6599462 0.82 BMP1 (0.81) BMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1373264-B1 3-HETEROCYCLYLPROPANOHYDROXAMIC ACID AS PROCOLLAGEN C-PROTEINASE INHIBITORS PFIZER LTD (GB) 2004-12-22 EP disclosed
US-6821972-B2 ANTISCARRING AGENTS; WOUND HEALING AGENTS; ENZYME INHIBITORS PFIZER INC. 2004-11-23 US disclosed