Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.69 |
| ▸ | MEN1 | O00255 | 6/20 | 0.69 |
| ▸ | POLB | P06746 | 5/20 | 0.69 |
| ▸ | USP2 | O75604 | 2/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.69 |
| ▸ | RECQL | P46063 | 1/20 | 0.69 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 6/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.67 |
| ▸ | CRHBP | P24387 | 1/20 | 0.67 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.67 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.63 |
| ▸ | TNF | P01375 | 3/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6599741 | 1.00 | ALDH1A1 (0.69) | ALDH1A1KDM4EKMT2AMEN1POLB | |
| SCHEMBL6591443 | 0.90 | MEN1 (0.70) | ALDH1A1KDM4EKMT2AMEN1POLB | |
| SCHEMBL6591439 | 0.90 | MEN1 (0.70) | ALDH1A1KDM4EKMT2AMEN1POLB | |
| SCHEMBL6593389 | 0.89 | KMT2A (0.72) | ALDH1A1KDM4EKMT2AMEN1POLB | |
| SCHEMBL6593384 | 0.89 | KMT2A (0.72) | ALDH1A1KDM4EKMT2AMEN1POLB | |
| SCHEMBL6594186 | 0.87 | MEN1 (0.72) | ALDH1A1KDM4EKMT2AMEN1POLB | |
| SCHEMBL6594182 | 0.87 | MEN1 (0.72) | ALDH1A1KDM4EKMT2AMEN1POLB | |
| SCHEMBL6591484 | 0.85 | PSD (0.73) | ALDH1A1KDM4EKMT2AMEN1POLB | |
| SCHEMBL6591480 | 0.85 | PSD (0.73) | ALDH1A1KDM4EKMT2AMEN1POLB | |
| SCHEMBL6597397 | 0.85 | MEN1 (0.77) | ALDH1A1KDM4EKMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004016271-A1 | PYRIMIDONES AS ANTIVIRAL AGENTS | AXXIMA PHARMACEUTICALS AG (DE) | 2004-02-26 | — | — | WO | claimed |
| EP-1389461-A1 | Pyrimidones with antiviral properties | Axxima Pharmaceuticals Aktiengesellschaft (DE) | 2004-02-18 | — | — | EP | claimed |
| EP-1412349-A2 | PIPERAZINE OXYQUINOLINE (NAPHTHALINE) PLATELET ADENOSINE DIPHOSPHATE RECEPTOR ANTAGONISTS | Schering Aktiengesellschaft (DE) | 2004-04-28 | — | — | EP | disclosed |
| WO-2004016271-A1 | PYRIMIDONES AS ANTIVIRAL AGENTS | AXXIMA PHARMACEUTICALS AG (DE) | 2004-02-26 | — | — | WO | disclosed |
| EP-1389461-A1 | Pyrimidones with antiviral properties | Axxima Pharmaceuticals Aktiengesellschaft (DE) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002098856-A2 | PIPERAZINE OXYQUINOLINE (NAPHTHALINE) PLATELET ADENOSINE DIPHOSPHATE RECEPTOR ANTAGONISTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-12-12 | — | — | WO | disclosed |