Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.47 |
| ▸ | ECE1 | P42892 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 3/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.43 |
| ▸ | FAP | Q12884 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.42 |
| ▸ | BMP1 | P13497 | 1/20 | 0.42 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2492939 | 1.00 | NOD1 (0.47) | NOD1ECE1KMT2AALOX15BLM | |
| SCHEMBL8429139 | 1.00 | NOD1 (0.47) | NOD1ECE1KMT2AALOX15BLM | |
| SCHEMBL8430995 | 1.00 | NOD1 (0.47) | NOD1ECE1KMT2AALOX15BLM | |
| SCHEMBL27396227 | 1.00 | NOD1 (0.47) | NOD1ECE1KMT2AALOX15BLM | |
| SCHEMBL27396231 | 1.00 | NOD1 (0.47) | NOD1ECE1KMT2AALOX15BLM | |
| SCHEMBL4221433 | 1.00 | NOD1 (0.47) | NOD1ECE1KMT2AALOX15BLM | |
| SCHEMBL30844356 | 0.94 | BACE1 (0.46) | NOD1ECE1KMT2AALOX15BLM | |
| SCHEMBL29351532 | 0.93 | NOD1 (0.42) | NOD1ECE1KMT2AALOX15BLM | |
| SCHEMBL16566026 | 0.93 | BACE1 (0.48) | NOD1ECE1FOLH1NAALAD2BMP1 | |
| SCHEMBL29574819 | 0.93 | NOD1 (0.42) | NOD1ECE1KMT2AALOX15BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453803-A2 | TETRAHYDROCARBOZOLE DERIVATIVES AS LIGANDS FOR G-PROTEIN COUPLED RECEPTORS (GPCR) | Zentaris GmbH (DE) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003051837-A2 | TETRAHYDROCARBOZOLE DERIVATIVES AS LIGANDS FOR G-PROTEIN COUPLED RECEPTORS (GPCR) | ZENTARIS GMBH (DE) | 2003-06-26 | — | — | WO | disclosed |