Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 2/20 | 0.39 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7861857 | 0.75 | — | — | |
| SCHEMBL11330896 | 0.69 | TRIM24 (0.50) | TRIM24TRIM33ALDH1A1KMT2AMAPT | |
| SCHEMBL1539236 | 0.68 | TRIM24 (0.43) | TRIM24TRIM33ALDH1A1KMT2AMAPT | |
| SCHEMBL1539198 | 0.68 | TRIM24 (0.43) | TRIM24TRIM33ALDH1A1KMT2AMAPT | |
| SCHEMBL1539169 | 0.68 | TRIM24 (0.43) | TRIM24TRIM33ALDH1A1KMT2AMAPT | |
| SCHEMBL11330899 | 0.67 | TRIM24 (0.48) | TRIM24TRIM33ALDH1A1KMT2AMAPT | |
| SCHEMBL2138928 | 0.67 | — | — | |
| SCHEMBL7774044 | 0.67 | — | — | |
| Cyclohexane SCHEMBL17939525 | 0.67 | — | — | |
| SCHEMBL24304032 | 0.66 | KMT2A (0.54) | TRIM24TRIM33ALDH1A1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1461320-A4 | ENANTIOSELECTIVE TRANSFORMATION OF ALFA,BETA-UNSATURATED KETONES USING CHIRAL ORGANIC CATALYSTS | CALIFORNIA INST OF TECHN (US) | 2004-12-08 | — | — | EP | disclosed |
| EP-1461320-A2 | ENANTIOSELECTIVE TRANSFORMATION OF ALFA,BETA-UNSATURATED KETONES USING CHIRAL ORGANIC CATALYSTS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2004-09-29 | — | — | EP | disclosed |
| WO-2003047740-A2 | ENANTIOSELECTIVE TRANSFORMATION OF α,β-UNSATURATED KETONES USING CHIRAL ORGANIC CATALYSTS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2003-06-12 | — | — | WO | disclosed |