Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.45 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6600485 | 1.00 | KMT2A (0.49) | KMT2AMEN1KCNN4KCNA3MAPT | |
| SCHEMBL6605034 | 0.86 | KMT2A (0.51) | KMT2AMEN1KCNN4KCNA3MAPT | |
| SCHEMBL6605044 | 0.86 | KMT2A (0.51) | KMT2AMEN1KCNN4KCNA3MAPT | |
| SCHEMBL6600501 | 0.82 | KMT2A (0.46) | KMT2AMEN1KCNN4KCNA3MAPT | |
| SCHEMBL6600502 | 0.82 | KMT2A (0.46) | KMT2AMEN1KCNN4KCNA3MAPT | |
| SCHEMBL6602030 | 0.77 | KCNN4 (0.48) | KMT2AMEN1KCNN4KCNA3MAPT | |
| SCHEMBL6602025 | 0.77 | KCNN4 (0.48) | KMT2AMEN1KCNN4KCNA3MAPT | |
| SCHEMBL1495922 | 0.75 | KCNN4 (0.64) | KMT2AMEN1KCNN4KCNA3MAPT | |
| SCHEMBL6329164 | 0.75 | ALDH1A1 (0.42) | KMT2AMAPTTSHRLMNANPC1 | |
| SCHEMBL1495972 | 0.75 | KMT2A (0.47) | KMT2AMEN1KCNN4KCNA3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877736-B1 | BENZAZEPINE DERIVATIVES WITH VASOPRESSIN AGONISTIC ACTIVITY | OTSUKA PHARMA CO LTD (JP) | 2004-04-21 | — | — | EP | disclosed |
| US-6096736-A | Benzazepine derivatives with vasopressin agonistic activity | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 2000-08-01 | — | — | US | disclosed |