Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 5/20 | 0.64 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.60 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.60 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.60 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.60 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.60 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5154912 | 0.99 | HTR3A (0.62) | HTR3ACHRNA7KCNH2CHRM4CHRM5 | |
| SCHEMBL4704458 | 0.80 | HTR3A (0.58) | HTR3ACHRNA7KCNH2CHRM4CHRM5 | |
| SCHEMBL4701401 | 0.79 | HTR3A (0.64) | HTR3ACHRNA7KCNH2CHRM4CHRM5 | |
| SCHEMBL373021 | 0.78 | HTR3A (1.00) | HTR3ACHRNA7KCNH2CHRM4CHRM5 | |
| SCHEMBL4699052 | 0.75 | HTR3A (1.00) | HTR3ACHRNA7KCNH2CHRM4CHRM5 | |
| SCHEMBL4699915 | 0.75 | HTR3A (0.69) | HTR3ACHRNA7KCNH2CHRM4CHRM5 | |
| SCHEMBL4700653 | 0.75 | HTR3A (0.69) | HTR3ACHRNA7KCNH2CHRM4CHRM5 | |
| SCHEMBL1459339 | 0.75 | HTR3A (1.00) | HTR3ACHRNA7KCNH2CHRM4CHRM5 | |
| Hydrochloric Acid SCHEMBL15663033 | 0.74 | HTR3A (0.97) | HTR3ACHRNA7KCNH2CHRM4CHRM5 | |
| SCHEMBL5248370 | 0.74 | HTR3A (0.77) | HTR3ACHRNA7KCNH2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289988-B1 | 1,4-DIAZABICYCLO 3.2.2]NONABENZOXAZOLE, -BENZOTHIAZOLE AND BENZIMIDAZOLE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI SYNTHELABO (FR) | 2004-05-19 | — | — | EP | disclosed |