SCHEMBL6600892

SCHEMBL6600892

[CH2]Cc1nc(C=CCC(C)C)oc1C

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.31
PPARG P37231 1/20 0.31
PPARA Q07869 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6600888 1.00 PTPN1 (0.31) PTPN1PPARGPPARA
SCHEMBL4479396 0.81 PTPN1 (0.35) PTPN1PPARGPPARA
SCHEMBL4479395 0.81 PTPN1 (0.35) PTPN1PPARGPPARA
SCHEMBL13328384 0.79
SCHEMBL4494634 0.75 PTPN1 (0.35) PTPN1PPARGPPARA
SCHEMBL6603658 0.72
SCHEMBL6603653 0.72
SCHEMBL13328389 0.69
SCHEMBL10480738 0.65
SCHEMBL13328387 0.62 PTPN1 (0.30) PTPN1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1403253-A1 NOVEL HETEROCYCLIC COMPOUND AND MEDICINAL USE THEREOF Kyoto Pharmaceutical Industries, Ltd. (JP) 2004-03-31 EP disclosed