Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4479395 | 1.00 | PTPN1 (0.35) | PTPN1PPARGPPARA | |
| SCHEMBL6600892 | 0.81 | PTPN1 (0.31) | PTPN1PPARGPPARA | |
| SCHEMBL6600888 | 0.81 | PTPN1 (0.31) | PTPN1PPARGPPARA | |
| SCHEMBL4482720 | 0.79 | PTPN1 (0.34) | PTPN1PPARG | |
| SCHEMBL4482725 | 0.79 | PTPN1 (0.34) | PTPN1PPARG | |
| SCHEMBL3286303 | 0.79 | PTPN1 (0.39) | PTPN1PPARGPPARA | |
| SCHEMBL3286301 | 0.79 | PTPN1 (0.39) | PTPN1PPARGPPARA | |
| SCHEMBL13328384 | 0.76 | — | — | |
| SCHEMBL4494634 | 0.76 | PTPN1 (0.35) | PTPN1PPARGPPARA | |
| SCHEMBL4491644 | 0.71 | RAB9A (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7557123-B2 | Heterocyclic compound and medicinal use thereof | KYOTO PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2009-07-07 | — | — | US | disclosed |
| US-20040220215-A1 | Novel heterocyclic compound and medicinal use thereof | KYOTO PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2004-11-04 | — | — | US | disclosed |
| EP-1403253-A1 | NOVEL HETEROCYCLIC COMPOUND AND MEDICINAL USE THEREOF | Kyoto Pharmaceutical Industries, Ltd. (JP) | 2004-03-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040220215-A1 | Novel heterocyclic compound and medicinal use thereof | GPR119, INSR, GLP1R | PTPN1 750/4885PPARG 6/4885PPARA 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.