Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 9/20 | 0.41 |
| ▸ | FNTB | P49356 | 9/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | GRK2 | P25098 | 1/20 | 0.35 |
| ▸ | GRK5 | P34947 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6601473 | 0.92 | DRD2 (0.40) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL6606446 | 0.86 | FNTA (0.45) | FNTAFNTBPGGT1BHDAC1 | |
| SCHEMBL6755039 | 0.85 | FNTA (0.54) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL6757415 | 0.83 | FNTA (0.42) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL6602181 | 0.83 | FNTA (0.41) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL6755034 | 0.81 | FNTA (0.41) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL6756401 | 0.80 | FNTA (0.40) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL6600844 | 0.80 | FNTA (0.45) | FNTAFNTBPGGT1BHDAC1 | |
| SCHEMBL6755031 | 0.79 | FNTA (0.40) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL6601136 | 0.78 | FNTA (0.41) | FNTAFNTBPGGT1BCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1395581-A2 | NOVEL BENZOTHIENYL OR INDOLE DERIVATIVES, PREPARATION AND USE THEREOF AS INHIBITORS OF PRENYL TRANSFERASE PROTEINS | PIERRE FABRE MEDICAMENT (FR) | 2004-03-10 | — | — | EP | claimed |
| WO-2002098852-A2 | NOVEL BENZOTHIENYL OR INDOLE DERIVATIVES, AND USE THEREOF AS INHIBITORS OF PRENYL TRANSFERASE PROTEINS | PIERRE FABRE MEDICAMENT (FR) | 2002-12-12 | — | — | WO | claimed |