Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.67 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.60 |
| ▸ | BCHE | P06276 | 3/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.54 |
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2937482 | 0.83 | AOC3 (0.73) | AOC3SIGMAR1BCHETAAR1CHRM2 | |
| SCHEMBL27366013 | 0.82 | HTR2A (0.64) | AOC3SIGMAR1BCHECHRM2HTR2A | |
| Hydrochloric Acid SCHEMBL8509376 | 0.81 | AOC3 (0.71) | AOC3SIGMAR1BCHETAAR1CHRM2 | |
| SCHEMBL4514454 | 0.81 | CHRM2 (0.67) | AOC3BCHETAAR1CHRM2ACHE | |
| SCHEMBL13579948 | 0.81 | BCHE (0.69) | AOC3SIGMAR1BCHECHRM2CYP1A2 | |
| SCHEMBL31618107 | 0.80 | HTR2A (0.51) | AOC3SIGMAR1HTR2AIDO1CYP1A2 | |
| SCHEMBL27375670 | 0.80 | AOC3 (0.64) | AOC3SIGMAR1BCHETAAR1CHRM2 | |
| SCHEMBL28858018 | 0.78 | TAAR1 (0.75) | AOC3SIGMAR1TAAR1CHRM2KCNH2 | |
| SCHEMBL6601574 | 0.77 | AOC3 (0.65) | AOC3SIGMAR1BCHETAAR1CHRM2 | |
| SCHEMBL158584 | 0.77 | TAAR1 (0.67) | AOC3SIGMAR1TAAR1CHRM2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1417190-A1 | SUBSTITUTED PIPERAZINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR | Amgen Inc. (US) | 2004-05-12 | — | — | EP | disclosed |
| WO-2003009850-A1 | SUBSTITUTED PIPERAZINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR | AMGEN INC. (US) | 2003-02-06 | — | — | WO | disclosed |