Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 18/20 | 0.61 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.41 |
| ▸ | CSNK1E | P49674 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3889529 | 0.78 | MAPK14 (0.69) | MAPK14CSNK1DCSNK1E | |
| SCHEMBL6502533 | 0.77 | MAPK14 (0.65) | MAPK14CSNK1DCSNK1E | |
| SCHEMBL11464007 | 0.77 | MAPK14 (0.56) | MAPK14TRPM8 | |
| SCHEMBL6280887 | 0.76 | MAPK14 (1.00) | MAPK14 | |
| SCHEMBL6284207 | 0.76 | MAPK14 (0.69) | MAPK14CSNK1DCSNK1E | |
| SCHEMBL6605134 | 0.75 | MAPK14 (0.53) | MAPK14 | |
| SCHEMBL6280916 | 0.75 | MAPK14 (0.67) | MAPK14CSNK1DCSNK1ENPC1RAB9A | |
| SCHEMBL30242346 | 0.73 | MAPK14 (1.00) | MAPK14CSNK1DCSNK1E | |
| SCHEMBL9266009 | 0.72 | ACHE (0.44) | NPC1RAB9A | |
| SCHEMBL3886214 | 0.71 | MAPK14 (0.76) | MAPK14CSNK1DCSNK1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1402900-A1 | MEDICINAL COMPOSITIONS | Takeda Chemical Industries, Ltd. (JP) | 2004-03-31 | — | — | EP | disclosed |