Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.37 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.37 |
| ▸ | CCKBR | P32239 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | TACR2 | P21452 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7639942 | 0.93 | ITGB3 (0.45) | ITGB3ITGA2BSIGMAR1GRM2 | |
| SCHEMBL6604885 | 0.93 | ITGB3 (0.41) | ITGB3ITGA2BSIGMAR1HTR1ADRD4 | |
| SCHEMBL6601558 | 0.92 | ITGB3 (0.53) | ITGB3ITGA2BSIGMAR1GRM2 | |
| SCHEMBL6601465 | 0.91 | ITGB3 (0.60) | ITGB3ITGA2BSIGMAR1HTR1AGRM2 | |
| SCHEMBL6605806 | 0.90 | ITGB3 (0.52) | ITGB3ITGA2BSIGMAR1HTR1AGRM2 | |
| SCHEMBL6600621 | 0.89 | ITGB3 (0.48) | ITGB3ITGA2BSIGMAR1DRD4GRM2 | |
| SCHEMBL6604884 | 0.88 | ITGB3 (0.42) | ITGB3ITGA2BSIGMAR1GRM2 | |
| SCHEMBL6604918 | 0.88 | ITGB3 (0.53) | ITGB3ITGA2BSIGMAR1GRM2 | |
| SCHEMBL6601206 | 0.88 | ITGB3 (0.51) | ITGB3ITGA2BSIGMAR1GRM2 | |
| SCHEMBL6600953 | 0.88 | ITGB3 (0.49) | ITGB3ITGA2BSIGMAR1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741133-B1 | Adhesion receptor antagonists | MERCK PATENT GMBH (DE) | 2004-01-28 | — | — | EP | disclosed |
| EP-0741133-A2 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1996-11-06 | — | — | EP | disclosed |