Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 16/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 10/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6284152 | 1.00 | ADRB3 (0.47) | ADRB3PTGS2ADRB1ADRB2PTGS1 | |
| SCHEMBL6284156 | 1.00 | ADRB3 (0.47) | ADRB3PTGS2ADRB1ADRB2PTGS1 | |
| SCHEMBL6279899 | 0.94 | ADRB3 (0.45) | ADRB3PTGS2ADRB1ADRB2 | |
| SCHEMBL6279905 | 0.94 | ADRB3 (0.45) | ADRB3PTGS2ADRB1ADRB2 | |
| SCHEMBL6284449 | 0.92 | ADRB3 (0.44) | ADRB3ADRB1ADRB2 | |
| SCHEMBL6284439 | 0.92 | ADRB3 (0.44) | ADRB3ADRB1ADRB2 | |
| SCHEMBL6283986 | 0.91 | PTGS2 (0.46) | ADRB3PTGS2ADRB1ADRB2 | |
| SCHEMBL6283980 | 0.91 | PTGS2 (0.46) | ADRB3PTGS2ADRB1ADRB2 | |
| SCHEMBL6277922 | 0.90 | ADRB3 (0.42) | ADRB3PTGS2ADRB1ADRB2PTGS1 | |
| SCHEMBL6277919 | 0.90 | ADRB3 (0.42) | ADRB3PTGS2ADRB1ADRB2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389202-B1 | 2,6-SUBSTITUTED CHROMAN DERIVATIVES USEFUL AS BETA-3 ADRENORECEPTOR AGONISTS | BAYER PHARMACEUTICALS CORP (US) | 2004-09-29 | — | — | EP | claimed |