Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 7/20 | 0.49 |
| ▸ | PPARG | P37231 | 7/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6293717 | 0.90 | PPARG (0.50) | HSD17B10LMNATARBP2PPARAPPARG | |
| SCHEMBL6290491 | 0.89 | HSD17B10 (0.55) | HSD17B10LMNATARBP2PPARAPPARG | |
| SCHEMBL6289197 | 0.88 | PPARG (0.51) | PPARAPPARGPOLBTP53 | |
| SCHEMBL6293798 | 0.87 | PPARA (0.53) | PPARAPPARG | |
| SCHEMBL3578702 | 0.87 | PPARG (0.55) | TARBP2PPARAPPARGPOLBTP53 | |
| SCHEMBL821405 | 0.87 | PPARG (0.59) | PPARAPPARGHPGD | |
| SCHEMBL3584058 | 0.86 | PPARG (0.45) | HSD17B10LMNAPPARAPPARGPOLB | |
| SCHEMBL6289729 | 0.86 | MEN1 (0.53) | HSD17B10LMNATARBP2PPARAPPARG | |
| SCHEMBL13807058 | 0.86 | PPARG (0.48) | PPARAPPARG | |
| SCHEMBL3991636 | 0.85 | PPARG (0.53) | HSD17B10TARBP2PPARAPPARGPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1398313-A1 | NOVEL HETEROCYCLIC DERIVATIVES AND MEDICINAL USE THEREOF | Kyoto Pharmaceutical Industries, Ltd. (JP) | 2004-03-17 | — | — | EP | disclosed |