Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.45 |
| ▸ | RELA | Q04206 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5385363 | 0.99 | MAPT (0.44) | MAPTKMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5389920 | 0.81 | NPC1 (0.53) | MAPTKMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6599831 | 0.80 | MAPT (0.58) | MAPTKMT2ARAB9ANPC1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5385836 | 0.79 | MAPT (0.57) | MAPTKMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7549919 | 0.78 | MAPT (0.39) | MAPTKMT2ARAB9ANPC1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7552145 | 0.77 | MAPT (0.38) | MAPTKMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL19405165 | 0.75 | NOS1 (0.55) | KCNH2 | |
| SCHEMBL2777995 | 0.74 | NOS1 (0.62) | KCNH2 | |
| SCHEMBL8188443 | 0.73 | NPC1 (0.55) | MAPTKMT2ARAB9ANPC1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2675849 | 0.73 | NOS1 (0.62) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1265891-B1 | NOVEL LIPOIC ACID HETEROCYCLIC OR BENZENE DERIVATIVES, PREPARATION AND USE THEREOF AS MEDICINES | CONSEILS DE RECH SET D APPLIC (FR) | 2004-12-29 | — | — | EP | disclosed |