⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6602891 | 0.79 | — | — | |
| SCHEMBL3554335 | 0.75 | — | — | |
| SCHEMBL1179556 | 0.71 | — | — | |
| SCHEMBL1776011 | 0.65 | ALOX15 (0.32) | — | |
| SCHEMBL10907881 | 0.65 | KDM4E (0.31) | — | |
| SCHEMBL27343897 | 0.64 | — | — | |
| SCHEMBL6460560 | 0.63 | — | — | |
| SCHEMBL24892721 | 0.62 | — | — | |
| SCHEMBL3465520 | 0.62 | — | — | |
| SCHEMBL28818017 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1062212-B1 | HETEROCYCLYL ANTHRACYCLINONE DERIVATIVES | PHARMACIA ITALIA SPA (IT) | 2004-05-12 | — | — | EP | disclosed |
| US-6316451-B1 | AMYLOIDOSIS | PHARMACIA & UPJOHN S.P.A. (IT) | 2001-11-13 | — | — | US | disclosed |
| EP-1062212-A1 | HETEROCYCLYL ANTHRACYCLINONE DERIVATIVES | PHARMACIA & UPJOHN S.p.A. (IT) | 2000-12-27 | — | — | EP | disclosed |
| WO-1999046253-A1 | HETEROCYCLYL ANTHRACYCLINONE DERIVATIVES | PHARMACIA & UPJOHN S.P.A. (IT) | 1999-09-16 | — | — | WO | disclosed |