Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 8/20 | 0.52 |
| ▸ | FAAH | O00519 | 6/20 | 0.52 |
| ▸ | LIPC | P11150 | 2/20 | 0.48 |
| ▸ | LIPE | Q05469 | 2/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | ABHD16A | O95870 | 2/20 | 0.44 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.42 |
| ▸ | LPL | P06858 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6600717 | 0.87 | MGLL (0.52) | MGLLFAAHLIPCLIPEBCHE | |
| Trifluoroacetic Acid SCHEMBL6601602 | 0.83 | MGLL (0.50) | MGLLFAAHLIPCLIPEBCHE | |
| Trifluoroacetic Acid SCHEMBL6601176 | 0.83 | MGLL (0.50) | MGLLFAAHLIPCLIPEBCHE | |
| Trifluoroacetic Acid SCHEMBL6601314 | 0.81 | MGLL (0.48) | MGLLFAAHLIPCLIPEBCHE | |
| Trifluoroacetic Acid SCHEMBL6599045 | 0.81 | MGLL (0.48) | MGLLFAAHLIPCLIPEBCHE | |
| Trifluoroacetic Acid SCHEMBL6606875 | 0.81 | MGLL (0.50) | MGLLFAAHLIPCLIPEBCHE | |
| SCHEMBL7043150 | 0.80 | MGLL (0.63) | MGLLFAAHLIPCLIPEBCHE | |
| Trifluoroacetic Acid SCHEMBL6599840 | 0.79 | MGLL (0.48) | MGLLFAAHLIPCLIPEABHD16A | |
| Trifluoroacetic Acid SCHEMBL6604365 | 0.79 | MGLL (0.46) | MGLLFAAHLIPCLIPEBCHE | |
| Trifluoroacetic Acid SCHEMBL6604040 | 0.79 | MGLL (0.46) | MGLLFAAHLIPCLIPEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263745-B1 | SUBSTITUTED 3-PHENYL-5-ALKOXI-1,3,4-OXDIAZOL-2-ONE AND USE THEREOF FOR INHIBITING HORMONE-SENSITIVE LIPASE | AVENTIS PHARMA GMBH (DE) | 2004-05-19 | — | — | EP | disclosed |