Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | CDC25B | P30305 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ERN1 | O75460 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8817413 | 0.87 | KDM4E (0.53) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL6605876 | 0.86 | HPGD (0.57) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL1671183 | 0.84 | KDM4E (0.58) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL6603117 | 0.83 | HPGD (0.56) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL17509531 | 0.83 | KDM4E (0.56) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL7181506 | 0.81 | MEN1 (0.68) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL6604466 | 0.80 | KDM4E (0.53) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL5823725 | 0.80 | DHODH (0.47) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL7812363 | 0.80 | CYP1A2 (0.60) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL497405 | 0.80 | KMT2A (0.66) | KDM4EALDH1A1HPGDHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1119551-B1 | NAPHTHALENECARBOXAMIDES AS TACHYKININ RECEPTOR ANTAGONISTS | ASTRAZENECA AB (SE) | 2004-12-29 | — | — | EP | disclosed |
| EP-1433783-A2 | Naphthalenecarboxamides as tachykinin receptor antagonists | AstraZeneca AB (SE) | 2004-06-30 | — | — | EP | disclosed |
| US-6001883-A | SUBSTITUTED BENZOPHENONES OF GIVEN FORMULA, SUCH AS 6,6'-DIMETHYL-2,2',3',4'-TETRAMETHOXY-5-TRIFLUOROMETHYL-BENZOPHENONE; HIGHLY SYSTEMIC FUNGICIDES; CONTROLLING FUNGAL DISEASE SUCH AS POWDERY MILDEW IN PLANTS | AMERICAN CYANAMID COMPANY (US) | 1999-12-14 | — | — | US | disclosed |
| US-4745121-A | AMINE OR CARBOXAMIDE SUBSTITUTED | ICI AMERICAS INC. (US) | 1988-05-17 | — | — | US | disclosed |
| US-4590290-A | REACTING DIMETHYL SULFATE WITH G-HYDROXY-1-NAPHTHOIC ACID | AMERICAN CYANAMID COMPANY (US) | 1986-05-20 | — | — | US | disclosed |