Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 17/20 | 0.58 |
| ▸ | HTR2C | P28335 | 1/20 | 0.58 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6602556 | 0.88 | CHRNB4 (0.51) | MCHR1HTR2CCHRNB4CHRNA3 | |
| SCHEMBL6603095 | 0.84 | MCHR1 (0.60) | MCHR1HTR2C | |
| SCHEMBL6606152 | 0.83 | MCHR1 (0.65) | MCHR1HTR2C | |
| SCHEMBL6602549 | 0.81 | MCHR1 (0.59) | MCHR1HTR2CSLC2A1 | |
| SCHEMBL6925443 | 0.81 | MCHR1 (0.81) | MCHR1HTR2CSLC2A1 | |
| SCHEMBL6926161 | 0.78 | MCHR1 (0.76) | MCHR1HTR2C | |
| SCHEMBL6604490 | 0.78 | MCHR1 (0.64) | MCHR1HTR2C | |
| SCHEMBL6602562 | 0.78 | MCHR1 (0.75) | MCHR1HTR2CSLC2A1 | |
| SCHEMBL6605150 | 0.78 | MCHR1 (0.75) | MCHR1HTR2CSLC2A1 | |
| SCHEMBL6898082 | 0.78 | MCHR1 (0.78) | MCHR1HTR2CSLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1102535-A4 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORP (US) | 2004-09-29 | — | — | EP | disclosed |
| US-6399656-B1 | USING A BENZOPYRAN-3-CARBOXAMIDE COMPOUND | SMITHKLINE BEECHAM CORPORATION | 2002-06-04 | — | — | US | disclosed |
| EP-1102535-A2 | COMPOUNDS AND METHODS | SmithKline Beecham Corporation (US) | 2001-05-30 | — | — | EP | disclosed |
| WO-2000006085-A2 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-10 | — | — | WO | disclosed |