SCHEMBL660325

SCHEMBL660325

In1cnnn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL784622 0.97
SCHEMBL29061272 0.65
SCHEMBL29290128 0.65
SCHEMBL21111119 0.65 ALDH1A1 (1.00)
SCHEMBL21111106 0.61 ALDH1A1 (0.79)
SCHEMBL21111146 0.61 ALDH1A1 (0.79)
SCHEMBL28523954 0.60
SCHEMBL21111121 0.58 ALDH1A1 (0.68)
SCHEMBL2228169 0.58
SCHEMBL828913 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119709317-A Cinnamomum tenuifolium leaf essential oil and application thereof in preparation of Cinnamomum tenuifolium leaf essential oil preservative film 中国科学院西双版纳热带植物园 2025-03-28 CN disclosed
US-11572362-B2 Pyrrolo[1,2-b]pyridazine derivatives GILEAD SCIENCES, INC. (US) 2023-02-07 US disclosed
US-11566022-B2 3-(5-methoxy-1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof NOVARTIS AG (CH) 2023-01-31 US disclosed
EP-3998263-A1 TRICYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF Shanghai Jemincare Pharmaceuticals Co., Ltd. (CN) 2022-05-18 EP disclosed
WO-2021239133-A1 PYRIMIDINE COMPOUND AS AXL INHIBITOR 南京正大天晴制药有限公司 2021-12-02 WO disclosed
US-10915023-B2 Nitrogen heterocycle-containing monolayers on metal oxides for binding biopolymers INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2021-02-09 US disclosed
US-20200071333-A1 PYRROLO[1,2-b]PYRIDAZINE DERIVATIVES GILEAD SCIENCES, INC. 2020-03-05 US disclosed
WO-2019145360-A1 NOVEL COMPOUNDS FOR THE TREATMENT OF PARASITIC INFECTIONS GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2019-08-01 WO disclosed
US-20190177382-A1 VASCULAR ENDOTHELIAL GROWTH FACTOR ANTAGONISTS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES 2019-06-13 US disclosed
US-20190119471-A1 THERMOPLASTIC ELASTOMER COMPOSITION AND METHOD FOR PRODUCING THE SAME JXTG NIPPON OIL & ENERGY CORPORATION (JP) 2019-04-25 US disclosed
EP-1978365-A1 Reagent kit and method for measuring HCV antibody SYSMEX CORPORATION (JP) 2008-10-08 EP disclosed
US-20080227111-A1 REAGENT KIT AND METHOD FOR MEASURING HCV ANTIBODY SYSMEX CORPORATION (JP) 2008-09-18 US disclosed
US-20080138337-A1 CONNEXIN ENHANCES CHEMOTHERAPY-INDUCED APOPTOSIS IN HUMAN CANCER CELLS INHIBITING TUMOR CELL PROLIFERATION NORTHWEST HOSPITAL (US) 2008-06-12 US disclosed
US-20040180846-A1 Connexin enhances chemotherapy-induced apoptiosis in human cancer cells inhibiting tumor cell proliferation NORTHWEST HOSPITAL 2004-09-16 US disclosed
US-5981545-A FOR USE IN THE TREATMENT AND/OR PROPHYLAXIS OF DEMENTIA BEECHAM GROUP P.L.C. (GB) 1999-11-09 US disclosed
US-5837692-A ANTITUMOR AGENTS OF POLYPEPTIDES MERCOLA DAN (US) 1998-11-17 US disclosed
WO-1998023737-A9 PRODUCTION OF IN VIVO LABELED SINGLE CHAIN SYNTHETIC ANTIBODY FRAGMENTS 1998-09-17 WO disclosed
WO-1998023737-A1 PRODUCTION OF IN VIVO LABELED SINGLE CHAIN SYNTHETIC ANTIBODY FRAGMENTS UNIVERSITEIT VAN AMSTERDAM (NL) 1998-06-04 WO disclosed
EP-0427390-B1 Azabicyclic compounds, process and intermediates for their preparation and pharmaceutical compositions containing them BEECHAM GROUP PLC (GB) 1996-03-27 EP disclosed
EP-0427390-A2 Azabicyclic compounds, process and intermediates for their preparation and pharmaceutical compositions containing them BEECHAM GROUP PLC (GB) 1991-05-15 EP disclosed