Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 20/20 | 0.70 |
| ▸ | MMP2 | P08253 | 2/20 | 0.63 |
| ▸ | MMP3 | P08254 | 1/20 | 0.61 |
| ▸ | MMP9 | P14780 | 1/20 | 0.61 |
| ▸ | MMP13 | P45452 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6603347 | 0.94 | BMP1 (0.67) | BMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL6599667 | 0.93 | BMP1 (0.66) | BMP1 | |
| SCHEMBL6597122 | 0.90 | BMP1 (0.55) | BMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL6596928 | 0.84 | BMP1 (0.53) | BMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL6600479 | 0.84 | BMP1 (0.72) | BMP1 | |
| SCHEMBL6598828 | 0.84 | BMP1 (0.53) | BMP1 | |
| SCHEMBL6599842 | 0.83 | BMP1 (0.74) | BMP1MMP3 | |
| SCHEMBL5408271 | 0.82 | BMP1 (0.72) | BMP1MMP2MMP3 | |
| SCHEMBL5405173 | 0.82 | BMP1 (0.72) | BMP1MMP2MMP3 | |
| SCHEMBL6598591 | 0.82 | BMP1 (1.00) | BMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373264-B1 | 3-HETEROCYCLYLPROPANOHYDROXAMIC ACID AS PROCOLLAGEN C-PROTEINASE INHIBITORS | PFIZER LTD (GB) | 2004-12-22 | — | — | EP | disclosed |
| US-6821972-B2 | ANTISCARRING AGENTS; WOUND HEALING AGENTS; ENZYME INHIBITORS | PFIZER INC. | 2004-11-23 | — | — | US | disclosed |