Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6607139 | 0.82 | PTGDR2 (0.51) | POLBATMPTGDR2MAPTRAB9A | |
| SCHEMBL18453732 | 0.81 | POLB (0.60) | ARPOLBATMPTGDR2NPC1 | |
| SCHEMBL7862574 | 0.76 | POLB (0.66) | ARPOLBATMPTGDR2NPC1 | |
| SCHEMBL20892555 | 0.75 | POLB (0.53) | ARPOLBATMPTGDR2NPC1 | |
| SCHEMBL20545506 | 0.74 | PTGDR2 (0.58) | ARPOLBPTGDR2NPC1MAPT | |
| SCHEMBL12195240 | 0.72 | AR (0.69) | ARPOLBPTGDR2MAPTRAB9A | |
| SCHEMBL20545517 | 0.71 | ALDH1A1 (0.54) | POLBPTGDR2MAPTALDH1A1LMNA | |
| SCHEMBL6604484 | 0.71 | BCHE (0.58) | ARNPC1MAPTRAB9ACYP1A2 | |
| SCHEMBL6604274 | 0.71 | BCHE (0.58) | ARNPC1MAPTRAB9ACYP1A2 | |
| SCHEMBL6603620 | 0.71 | BCHE (0.58) | ARNPC1MAPTRAB9ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6787561-B1 | HYPERLIPIDEMIA, ARTERIOSCLEROSIS; ORAL ADMINISTRATION; SUPPRESSING THE FORMING OF MACROPHAGES | FUJI PHOTO FILM CO., LTD. (JP) | 2004-09-07 | — | — | US | disclosed |
| EP-1197493-B1 | BENZIMIDAZOLE COMPOUNDS | FUJI PHOTO FILM CO LTD (JP) | 2004-03-24 | — | — | EP | disclosed |
| EP-1197493-A1 | BENZIMIDAZOLE COMPOUNDS | FUJI PHOTO FILM CO., LTD. (JP) | 2002-04-17 | — | — | EP | disclosed |