Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.79 |
| ▸ | BCHE | P06276 | 1/20 | 0.73 |
| ▸ | NPC1 | O15118 | 4/20 | 0.70 |
| ▸ | RAB9A | P51151 | 3/20 | 0.70 |
| ▸ | LMNA | P02545 | 5/20 | 0.68 |
| ▸ | AR | P10275 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6605155 | 1.00 | EPHX2 (0.79) | EPHX2BCHENPC1RAB9ALMNA | |
| SCHEMBL6608285 | 1.00 | EPHX2 (0.79) | EPHX2BCHENPC1RAB9ALMNA | |
| SCHEMBL6603238 | 0.98 | EPHX2 (0.82) | EPHX2BCHENPC1RAB9ALMNA | |
| SCHEMBL14303260 | 0.94 | BCHE (0.83) | EPHX2BCHENPC1RAB9ALMNA | |
| SCHEMBL14303261 | 0.94 | BCHE (0.83) | EPHX2BCHENPC1RAB9ALMNA | |
| SCHEMBL14304387 | 0.94 | BCHE (0.83) | EPHX2BCHENPC1RAB9ALMNA | |
| SCHEMBL14304381 | 0.94 | BCHE (0.83) | EPHX2BCHENPC1RAB9ALMNA | |
| SCHEMBL6141660 | 0.94 | BCHE (0.83) | EPHX2BCHENPC1RAB9ALMNA | |
| Bromide SCHEMBL5084026 | 0.92 | BCHE (0.80) | EPHX2BCHENPC1RAB9ALMNA | |
| SCHEMBL14304932 | 0.92 | BCHE (0.86) | EPHX2BCHENPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6787561-B1 | HYPERLIPIDEMIA, ARTERIOSCLEROSIS; ORAL ADMINISTRATION; SUPPRESSING THE FORMING OF MACROPHAGES | FUJI PHOTO FILM CO., LTD. (JP) | 2004-09-07 | — | — | US | disclosed |
| EP-1197493-B1 | BENZIMIDAZOLE COMPOUNDS | FUJI PHOTO FILM CO LTD (JP) | 2004-03-24 | — | — | EP | disclosed |
| EP-1197493-A1 | BENZIMIDAZOLE COMPOUNDS | FUJI PHOTO FILM CO., LTD. (JP) | 2002-04-17 | — | — | EP | disclosed |