Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 9/20 | 0.71 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5462174 | 0.84 | MAPK14 (1.00) | MAPK14MAPK11 | |
| SCHEMBL6604150 | 0.83 | MAPK14 (0.75) | MAPK14MAPK11 | |
| SCHEMBL6603105 | 0.82 | MAPK14 (0.74) | MAPK14MAPK11 | |
| SCHEMBL6608046 | 0.82 | MAPK14 (0.74) | MAPK14MAPK11 | |
| SCHEMBL5461304 | 0.81 | MAPK14 (0.81) | MAPK14MAPK11 | |
| SCHEMBL5466901 | 0.80 | MAPK14 (0.84) | MAPK14MAPK11 | |
| SCHEMBL6629040 | 0.79 | MAPK14 (0.63) | MAPK14MAPK11 | |
| SCHEMBL6605697 | 0.79 | MAPK14 (0.71) | MAPK14MAPK11 | |
| SCHEMBL4700889 | 0.78 | MAPK14 (0.60) | MAPK14CYP19A1NPC1SMN1; SMN2POLB | |
| SCHEMBL5462093 | 0.78 | MAPK14 (0.77) | MAPK14MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1436269-A1 | OXADIAZOLYL-BIPHENYLCARBOXAMIDES AND THEIR USE AS P38 KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2004-07-14 | — | — | EP | disclosed |
| WO-2003033482-A1 | OXADIAZOLYL-BIPHENYLCARBOXAMIDES AND THEIR USE AS P38 KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2003-04-24 | — | — | WO | disclosed |