Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 17/20 | 0.74 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.64 |
| ▸ | LCK | P06239 | 2/20 | 0.60 |
| ▸ | CSF1R | P07333 | 1/20 | 0.58 |
| ▸ | HTR1D | P28221 | 2/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6604150 | 0.94 | MAPK14 (0.75) | MAPK14MAPK11LCK | |
| SCHEMBL6603105 | 0.93 | MAPK14 (0.74) | MAPK14MAPK11LCK | |
| SCHEMBL6605697 | 0.88 | MAPK14 (0.71) | MAPK14MAPK11LCKCSF1R | |
| SCHEMBL5462174 | 0.85 | MAPK14 (1.00) | MAPK14MAPK11 | |
| SCHEMBL6604294 | 0.82 | MAPK14 (0.71) | MAPK14MAPK11 | |
| SCHEMBL5466901 | 0.82 | MAPK14 (0.84) | MAPK14MAPK11 | |
| SCHEMBL5461304 | 0.80 | MAPK14 (0.81) | MAPK14MAPK11 | |
| SCHEMBL6615248 | 0.80 | MAPK14 (0.67) | MAPK14MAPK11LCK | |
| SCHEMBL5462093 | 0.79 | MAPK14 (0.77) | MAPK14MAPK11 | |
| SCHEMBL5464918 | 0.78 | MAPK14 (1.00) | MAPK14MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1436269-A1 | OXADIAZOLYL-BIPHENYLCARBOXAMIDES AND THEIR USE AS P38 KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2004-07-14 | — | — | EP | disclosed |
| WO-2003033482-A1 | OXADIAZOLYL-BIPHENYLCARBOXAMIDES AND THEIR USE AS P38 KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2003-04-24 | — | — | WO | disclosed |