Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.80 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.80 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | CCR5 | P51681 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1427564 | 0.98 | KDM4E (0.83) | KDM4ETDP1TRPV6TSHRMEN1 | |
| SCHEMBL19869956 | 0.88 | GAA (0.66) | KDM4ETDP1TRPV6MEN1KMT2A | |
| SCHEMBL18227502 | 0.86 | KDM4E (0.61) | KDM4ETDP1TRPV6MEN1KMT2A | |
| SCHEMBL4591936 | 0.84 | KDM4E (0.70) | KDM4ETDP1TRPV6TSHRMEN1 | |
| SCHEMBL1427948 | 0.83 | TDP1 (0.65) | KDM4ETDP1TSHRMEN1KMT2A | |
| SCHEMBL2760407 | 0.82 | MEN1 (0.62) | KDM4ETDP1TSHRMEN1KMT2A | |
| SCHEMBL9831262 | 0.82 | KDM4E (0.64) | KDM4ETDP1TSHRMEN1KMT2A | |
| SCHEMBL19086425 | 0.82 | KDM4E (0.61) | KDM4ETDP1TRPV6MEN1KMT2A | |
| SCHEMBL9829670 | 0.81 | KDM4E (0.66) | KDM4ETDP1TSHRMEN1KMT2A | |
| SCHEMBL3379362 | 0.81 | KMT2A (0.58) | KDM4ETDP1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244655-B1 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2004-02-18 | — | — | EP | disclosed |
| US-6620837-B1 | 1-Benzothiophene derivatives | ELI LILLY AND COMPANY | 2003-09-16 | — | — | US | disclosed |
| EP-1244655-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001036414-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2001-05-25 | — | — | WO | disclosed |