Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | GFER | P55789 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.41 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6592993 | 0.86 | MCHR1 (0.39) | KDM4EALDH1A1MAPTHTTHSD17B10 | |
| SCHEMBL24463199 | 0.79 | MCHR1 (0.40) | KDM4EALDH1A1MAPTHTTHSD17B10 | |
| SCHEMBL12402264 | 0.79 | MAPT (0.50) | KDM4EALDH1A1MAPTHTTHSD17B10 | |
| SCHEMBL6607679 | 0.79 | MCHR1 (0.40) | KDM4EALDH1A1MAPTHTTHSD17B10 | |
| SCHEMBL6233721 | 0.78 | KDM4E (0.44) | KDM4EALDH1A1MAPTHTTHSD17B10 | |
| SCHEMBL2734327 | 0.78 | KDM4E (0.52) | KDM4EALDH1A1MAPTHTTHSD17B10 | |
| SCHEMBL297992 | 0.77 | KDM4E (0.60) | KDM4EALDH1A1MAPTHTTHSD17B10 | |
| Hydrochloric Acid SCHEMBL6623126 | 0.77 | KDM4E (0.51) | KDM4EALDH1A1MAPTHTTHSD17B10 | |
| Hydrochloric Acid SCHEMBL16633753 | 0.75 | KDM4E (0.63) | KDM4EALDH1A1MAPTHTTHSD17B10 | |
| SCHEMBL6230772 | 0.75 | SMN1; SMN2 (0.58) | KDM4EALDH1A1MAPTHTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007088277-A1 | TRICYCLIC Ν-HETEROARYL-CARBOXAMIDE DERIVATIVES CONTAINING A BENZIMIDAZOLE UNIT, METHOD FOR PREPARING SAME AND THEIR THERAPEUTIC USE | SANOFI-AVENTIS (FR) | 2007-08-09 | — | — | WO | disclosed |
| EP-1373252-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | Aventis Pharma S.A. (FR) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002076975-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | AVENTIS PHARMA S.A. (FR) | 2002-10-03 | — | — | WO | disclosed |