Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.33 |
| ▸ | RAB9A | P51151 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24463199 | 0.79 | MCHR1 (0.40) | MCHR1HDAC6KDM4EHSD17B10MAPT | |
| SCHEMBL6604741 | 0.79 | KDM4E (0.45) | MCHR1HDAC6KDM4EHSD17B10MAPT | |
| SCHEMBL12402264 | 0.79 | MAPT (0.50) | MCHR1HDAC6KDM4EHSD17B10MAPT | |
| SCHEMBL14685203 | 0.74 | SMN1; SMN2 (0.57) | KDM4EHSD17B10MAPTSMN1; SMN2RAB9A | |
| SCHEMBL32661807 | 0.73 | CA12 (0.45) | MCHR1HDAC6RAB9AALDH1A1NPC1 | |
| SCHEMBL13895118 | 0.67 | MCHR1 (0.50) | MCHR1KDM4EHSD17B10RAB9AALDH1A1 | |
| SCHEMBL5610646 | 0.66 | SMN1; SMN2 (0.33) | MCHR1KDM4EHSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL24402332 | 0.62 | CSNK2A2 (0.39) | MCHR1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL1374758 | 0.61 | SMN1; SMN2 (0.53) | KDM4EHSD17B10MAPTSMN1; SMN2RAB9A | |
| SCHEMBL6599912 | 0.60 | LMNA (0.37) | MCHR1MAPTRAB9AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373252-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | Aventis Pharma S.A. (FR) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002076975-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | AVENTIS PHARMA S.A. (FR) | 2002-10-03 | — | — | WO | disclosed |