Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 16/20 | 0.52 |
| ▸ | CCR5 | P51681 | 2/20 | 0.52 |
| ▸ | EDNRA | P25101 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5103019 | 0.89 | CCR4 (0.65) | CCR4CCR5KDM4EMEN1KMT2A | |
| SCHEMBL5111658 | 0.80 | CCR4 (0.68) | CCR4CCR5MEN1KMT2A | |
| SCHEMBL5105623 | 0.76 | CCR4 (0.72) | CCR4CCR5EDNRAMEN1KMT2A | |
| SCHEMBL5105223 | 0.72 | CCR4 (1.00) | CCR4CCR5EDNRA | |
| SCHEMBL5106090 | 0.72 | CCR4 (1.00) | CCR4CCR5EDNRAKDM4E | |
| SCHEMBL5617358 | 0.72 | KDM4E (0.45) | CCR4CCR5KDM4EMEN1KMT2A | |
| SCHEMBL5111482 | 0.71 | CCR4 (0.76) | CCR4CCR5EDNRAMEN1KMT2A | |
| SCHEMBL6181970 | 0.71 | CCR4 (0.76) | CCR4CCR5EDNRAKDM4EMEN1 | |
| SCHEMBL6039005 | 0.71 | CCR4 (0.73) | CCR4CCR5EDNRAMEN1KMT2A | |
| SCHEMBL5617402 | 0.70 | KDM4E (0.54) | CCR4KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458715-A1 | NOVEL COMPOUNDS | AstraZeneca AB (SE) | 2004-09-22 | — | — | EP | claimed |
| WO-2003051870-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2003-06-26 | — | — | WO | claimed |