Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 18/20 | 0.65 |
| ▸ | CCR5 | P51681 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5111658 | 0.90 | CCR4 (0.68) | CCR4CCR5MEN1KMT2A | |
| SCHEMBL6604764 | 0.89 | CCR4 (0.52) | CCR4CCR5KDM4EMEN1KMT2A | |
| SCHEMBL5106090 | 0.81 | CCR4 (1.00) | CCR4CCR5KDM4E | |
| SCHEMBL5105223 | 0.81 | CCR4 (1.00) | CCR4CCR5 | |
| SCHEMBL5617358 | 0.78 | KDM4E (0.45) | CCR4CCR5KDM4EMEN1KMT2A | |
| SCHEMBL5103326 | 0.77 | CCR4 (0.48) | CCR4CCR5KDM4EMEN1KMT2A | |
| SCHEMBL6181633 | 0.77 | KDM4E (0.53) | CCR4KDM4EMEN1KMT2A | |
| SCHEMBL5106036 | 0.76 | CCR4 (0.74) | CCR4CCR5MEN1KMT2A | |
| SCHEMBL5617402 | 0.76 | KDM4E (0.54) | CCR4KDM4EMEN1KMT2A | |
| SCHEMBL6039005 | 0.75 | CCR4 (0.73) | CCR4CCR5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7410972-B2 | Compounds | ASTRAZENECA AB (SE) | 2008-08-12 | — | — | US | claimed |