Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 5/20 | 0.39 |
| ▸ | FNTB | P49356 | 5/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.36 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6756357 | 0.91 | FNTA (0.39) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL6601479 | 0.88 | CLK1 (0.40) | CLK1FNTAFNTBPGGT1BCYP11B1 | |
| SCHEMBL6758336 | 0.88 | DRD4 (0.41) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL6759286 | 0.87 | CYP11B1 (0.41) | CLK1FNTAFNTBPGGT1BCYP11B1 | |
| SCHEMBL6757432 | 0.87 | CXCR3 (0.41) | FNTAFNTBPGGT1B | |
| SCHEMBL6605046 | 0.85 | CYP11B1 (0.42) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL6756422 | 0.85 | FNTA (0.41) | CLK1FNTAFNTBPGGT1BCYP11B1 | |
| SCHEMBL6602531 | 0.84 | FNTA (0.41) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL6755031 | 0.83 | FNTA (0.40) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL6756429 | 0.83 | FNTA (0.41) | FNTAFNTBPGGT1BRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1395581-A2 | NOVEL BENZOTHIENYL OR INDOLE DERIVATIVES, PREPARATION AND USE THEREOF AS INHIBITORS OF PRENYL TRANSFERASE PROTEINS | PIERRE FABRE MEDICAMENT (FR) | 2004-03-10 | — | — | EP | claimed |
| WO-2002098852-A2 | NOVEL BENZOTHIENYL OR INDOLE DERIVATIVES, AND USE THEREOF AS INHIBITORS OF PRENYL TRANSFERASE PROTEINS | PIERRE FABRE MEDICAMENT (FR) | 2002-12-12 | — | — | WO | claimed |