Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | APEX1 | P27695 | 2/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7621081 | 0.98 | PIK3CD (0.43) | PIK3CDTSHRLMNACHRM2CHRM5 | |
| SCHEMBL7627567 | 0.78 | PIK3CD (0.42) | PIK3CDTSHRLMNACHRM2CHRM5 | |
| SCHEMBL6604973 | 0.77 | PIK3CD (0.48) | PIK3CDTSHRLMNACHRM2CHRM5 | |
| SCHEMBL7621090 | 0.76 | PIK3CD (0.47) | PIK3CDTSHRLMNACHRM2CHRM5 | |
| SCHEMBL7627564 | 0.73 | LMNA (0.44) | PIK3CDTSHRLMNACHRM2CHRM5 | |
| SCHEMBL510427 | 0.70 | — | — | |
| SCHEMBL261644 | 0.69 | PIK3CD (0.58) | PIK3CDTSHRLMNACHRM2CHRM5 | |
| SCHEMBL4278259 | 0.69 | KMT2A (0.59) | PIK3CDTSHRLMNACHRM2CHRM5 | |
| Ammonia Solution, Strong SCHEMBL9320676 | 0.69 | — | — | |
| Ammonia Solution, Strong SCHEMBL5668093 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1106614-B1 | 5-Membered heteroaryl substituted 1,4-dihydropyridine compounds as bradykinin antagonists | PFIZER (US) | 2004-01-07 | — | — | EP | disclosed |