Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | KRAS | P01116 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1640545 | 0.80 | APP (0.56) | ALDH1A1KDM4EUSP2CYP19A1MAPT | |
| SCHEMBL1413112 | 0.76 | GAA (0.51) | ALDH1A1KDM4EUSP2CYP19A1MAPT | |
| SCHEMBL18147051 | 0.75 | ALDH1A1 (0.51) | ALDH1A1KDM4EUSP2CYP19A1MAPT | |
| SCHEMBL11338264 | 0.75 | ALDH1A1 (0.47) | ALDH1A1KDM4EUSP2CYP19A1MAPT | |
| SCHEMBL7806591 | 0.75 | GAA (0.44) | ALDH1A1KDM4EUSP2CYP19A1MAPT | |
| SCHEMBL9398336 | 0.74 | MAPT (0.50) | ALDH1A1KDM4EUSP2CYP19A1MAPT | |
| SCHEMBL15486485 | 0.74 | ALDH1A1 (0.46) | ALDH1A1KDM4EUSP2CYP19A1MAPT | |
| SCHEMBL21672910 | 0.73 | ALDH1A1 (0.42) | ALDH1A1KDM4EUSP2CYP19A1MAPT | |
| Hydrochloric Acid SCHEMBL15486483 | 0.73 | ALDH1A1 (0.45) | ALDH1A1KDM4EUSP2CYP19A1MAPT | |
| SCHEMBL2119806 | 0.73 | ALDH1A1 (0.49) | ALDH1A1KDM4ECYP19A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1102535-A4 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORP (US) | 2004-09-29 | — | — | EP | disclosed |
| US-6399656-B1 | USING A BENZOPYRAN-3-CARBOXAMIDE COMPOUND | SMITHKLINE BEECHAM CORPORATION | 2002-06-04 | — | — | US | disclosed |
| EP-1102535-A2 | COMPOUNDS AND METHODS | SmithKline Beecham Corporation (US) | 2001-05-30 | — | — | EP | disclosed |
| WO-2000006085-A2 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-10 | — | — | WO | disclosed |