Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | SLC18A3 | Q16572 | 3/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 4/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL6601897 | 0.91 | PPARG (0.44) | HTR2ATAAR1SLC18A3EPHX1SIGMAR1 | |
| SCHEMBL27465388 | 0.80 | LOXL2 (0.48) | CYP2D6CYP1A2CYP2C19 | |
| SCHEMBL29158041 | 0.80 | CYP3A4 (0.46) | HTR2ATAAR1SLC18A3IDO1SIGMAR1 | |
| SCHEMBL2457986 | 0.80 | CYP3A4 (0.46) | HTR2ATAAR1SLC18A3IDO1SIGMAR1 | |
| SCHEMBL16434845 | 0.78 | LOXL2 (0.50) | TAAR1IDO1PPARGPPARACYP2D6 | |
| SCHEMBL25703539 | 0.78 | PPARG (0.42) | HTR2ATAAR1SLC18A3IDO1SIGMAR1 | |
| SCHEMBL5982885 | 0.78 | SLC18A3 (0.53) | SLC18A3EPHX1SIGMAR1CYP1A2 | |
| SCHEMBL3865414 | 0.78 | SLC18A3 (0.42) | TAAR1SLC18A3SIGMAR1GRIN2DGRIN3B | |
| SCHEMBL7991885 | 0.78 | TAAR1 (0.46) | TAAR1IDO1GRIN2DGRIN3BADRA1D | |
| SCHEMBL5678777 | 0.77 | EPHX1 (0.52) | TAAR1EPHX1SIGMAR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1397353-A1 | 2-(2,6-DISUBSTITUTED PHENYL)-4-ARYL-5-ALKYL-1,3-OXAZOLINE COMPOUNDS USEFUL AS INSECTICIDES AND ACARICIDES | Dow Agrosciences LLC (US) | 2004-03-17 | — | — | EP | disclosed |
| WO-2003000669-A1 | 2-(2,6-DISUBSTITUTED PHENYL)-4-ARYL-5-ALKYL-1,3-OXAZOLINE COMPOUNDS USEFUL AS INSECTICIDES AND ACARICIDES | DOW AGROSCIENCES LLC (US) | 2003-01-03 | — | — | WO | disclosed |