Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRB | P23467 | 9/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | HTT | P42858 | 5/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | JAK2 | O60674 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | XBP1 | P17861 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 2/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6605788 | 1.00 | PTPRB (0.42) | PTPRBALDH1A1HPGDHTTNPSR1 | |
| SCHEMBL6401305 | 0.95 | PTPRB (0.40) | PTPRBALDH1A1HPGDHTTNPSR1 | |
| SCHEMBL6399531 | 0.85 | CA2 (0.38) | PTPRBHPGDHTTNPSR1LMNA | |
| SCHEMBL6406008 | 0.83 | PPARA (0.48) | PTPRBALDH1A1HPGDHTTNPSR1 | |
| SCHEMBL6406011 | 0.83 | PPARA (0.48) | PTPRBALDH1A1HPGDHTTNPSR1 | |
| SCHEMBL7117234 | 0.77 | CTNNB1 (0.36) | KMT2AMEN1TP53ATMCTSS | |
| SCHEMBL7127966 | 0.75 | ATM (0.35) | KMT2AMEN1TP53ATMCTSS | |
| SCHEMBL6403235 | 0.75 | CTNNB1 (0.37) | KMT2AMEN1CA12 | |
| SCHEMBL6403233 | 0.74 | CTNNB1 (0.39) | KMT2AMEN1CA12 | |
| SCHEMBL6605239 | 0.74 | CYP2A6 (0.46) | KMT2AMEN1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289980-B1 | BICYCLYL OR HETEROBICYCLYLMETHANESULFONYLAMINO-SUBSTITUTED N-HYDROXYFORMAMIDES | SMITHKLINE BEECHAM PLC (GB) | 2004-11-17 | — | — | EP | disclosed |