Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 7/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.54 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.54 |
| ▸ | KDR | P35968 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6604498 | 0.93 | MCHR1 (0.55) | MCHR1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL6606130 | 0.90 | MCHR1 (0.62) | MCHR1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL6604490 | 0.87 | MCHR1 (0.64) | MCHR1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL2304880 | 0.85 | KCNQ3 (0.68) | MEN1KMT2AALDH1A1LMNAKCNQ3 | |
| SCHEMBL6926140 | 0.84 | MCHR1 (0.72) | MCHR1MEN1KMT2AALDH1A1KDR | |
| SCHEMBL6610208 | 0.84 | MCHR1 (0.63) | MCHR1ALDH1A1LMNAKDRMAPT | |
| SCHEMBL6925370 | 0.83 | MCHR1 (0.71) | MCHR1ALDH1A1KDRMAPTSMN1; SMN2 | |
| SCHEMBL6923988 | 0.83 | MCHR1 (0.71) | MCHR1ALDH1A1KDRSMN1; SMN2RAB9A | |
| SCHEMBL6928256 | 0.82 | MCHR1 (0.70) | MCHR1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7723668 | 0.82 | MCHR1 (0.61) | MCHR1MEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1102535-A4 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORP (US) | 2004-09-29 | — | — | EP | disclosed |
| US-6399656-B1 | USING A BENZOPYRAN-3-CARBOXAMIDE COMPOUND | SMITHKLINE BEECHAM CORPORATION | 2002-06-04 | — | — | US | disclosed |
| EP-1102535-A2 | COMPOUNDS AND METHODS | SmithKline Beecham Corporation (US) | 2001-05-30 | — | — | EP | disclosed |
| WO-2000006085-A2 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-10 | — | — | WO | disclosed |