Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 7/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 2/20 | 0.48 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.48 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6603098 | 0.93 | MCHR1 (0.52) | MCHR1SMN1; SMN2HTTMAPTMAPK1 | |
| SCHEMBL6606694 | 0.91 | MCHR1 (0.58) | MCHR1SMN1; SMN2HTTMAPTMAPK1 | |
| SCHEMBL6603095 | 0.88 | MCHR1 (0.60) | MCHR1SMN1; SMN2HTTMAPTMAPK1 | |
| SCHEMBL6925370 | 0.88 | MCHR1 (0.71) | MCHR1SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL6610208 | 0.86 | MCHR1 (0.63) | MCHR1SMN1; SMN2HTTMAPTMAPK1 | |
| SCHEMBL6923947 | 0.86 | MCHR1 (0.66) | MCHR1TSHRLMNACYP1A2CYP3A4 | |
| SCHEMBL6926140 | 0.82 | MCHR1 (0.72) | MCHR1SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL6605967 | 0.82 | MCHR1 (0.63) | MCHR1SMN1; SMN2HTTMAPTMAPK1 | |
| SCHEMBL6923988 | 0.81 | MCHR1 (0.71) | MCHR1SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL6928256 | 0.81 | MCHR1 (0.70) | MCHR1SMN1; SMN2MAPTMAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399656-B1 | USING A BENZOPYRAN-3-CARBOXAMIDE COMPOUND | SMITHKLINE BEECHAM CORPORATION | 2002-06-04 | — | — | US | disclosed |