Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NNMT | P40261 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28473659 | 0.98 | MAPT (0.53) | MAPTTDP1TUBB1PDE4DALDH1A1 | |
| Fumaric Acid SCHEMBL28256424 | 0.90 | MAPT (0.50) | MAPTTDP1TUBB1PDE4DALDH1A1 | |
| Succinic Acid SCHEMBL28257927 | 0.90 | MAPT (0.50) | MAPTTDP1TUBB1PDE4DALDH1A1 | |
| Maleic Acid SCHEMBL28866379 | 0.90 | MAPT (0.50) | MAPTTDP1TUBB1PDE4DALDH1A1 | |
| SCHEMBL11039311 | 0.89 | NNMT (0.52) | MAPTTDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL27906024 | 0.86 | MAPK1 (0.53) | MAPTTDP1PDE4DLMNAMAPK1 | |
| SCHEMBL15263986 | 0.85 | KDM4E (0.53) | MAPTTDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL4510130 | 0.85 | MAPT (0.51) | MAPTTDP1TUBB1ALDH1A1LMNA | |
| SCHEMBL9726919 | 0.83 | MAPT (0.58) | MAPTTDP1TUBB1PDE4DALDH1A1 | |
| SCHEMBL3421092 | 0.83 | MAPT (0.50) | MAPTTDP1TUBB1PDE4DALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103396397-A | lenalidomide derivatives and their use as medicaments | INST PHARM & TOXICOLOGY AMMS | 2013-11-20 | — | — | CN | claimed |
| CN-102850364-A | Derivative of Dysosma versipellis, and composition, preparation method and use thereof | SHANGHAI INST PHARM INDUSTRY | 2013-01-02 | — | — | CN | claimed |
| CN-102807514-A | Substituted phenylenediamine derivative and preparation method and application thereof | SU BIN | 2012-12-05 | — | — | CN | claimed |
| CN-102190632-A | 2,4,5-trisubstituted selenazole compounds and preparation method, compositions and application thereof | INST PHARM & TOXICOLOGY AMMS | 2011-09-21 | — | — | CN | claimed |
| CN-102105437-A | Adamantyl diamide derivatives and uses of same | LUNDBECK & CO AS H | 2011-06-22 | — | — | CN | claimed |
| CN-101987814-A | Method for preparing 3,4,5-trimethoxyphenol | KUNMING PHARMACEUTICAL CORP | 2011-03-23 | — | — | CN | claimed |
| CN-1948298-B | Dopamine D3 acceptor portion agonist and its application | UNIV SOUTHEAST | 2010-09-01 | — | — | CN | claimed |
| CN-101384544-A | Substituted cyclohexylmethyl derivatives | GRUENENTHAL GMBH (DE) | 2009-03-11 | — | — | CN | claimed |
| CN-100451004-C | Pyrimidine derivatives | ARENA PHARM INC (JP) | 2009-01-14 | — | — | CN | claimed |
| CN-100402534-C | Tricycle compounds and its application in making medicine | UNIV SOUTHEAST (CN) | 2008-07-16 | — | — | CN | claimed |
| CN-1143855-C | I (ortho)-anthranilamide derivatives as anti-coagulants | ���ֹɷݹ�˾ | 2004-03-31 | — | — | CN | claimed |
| EP-1294707-A2 | THIOPHENE DERIVATIVES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | Pharmacia Italia S.p.A. (IT) | 2003-03-26 | — | — | EP | claimed |
| WO-2001098290-A2 | THIOPHENE DERIVATIVES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | PHARMACIA ITALIA S.P.A. (IT) | 2001-12-27 | — | — | WO | claimed |
| CN-1325389-A | 2-aminothiazole derivatives, process for preparing the same and their use as antitumor agents | PHARMACIA & UPJOHN SPA (IT) | 2001-12-05 | — | — | CN | claimed |
| CN-1066448-C | Amide derivatives | OTSUKA PHARMA CO LTD (JP) | 2001-05-30 | — | — | CN | claimed |
| CN-1282329-A | I (ortho)-anthranilamide derivatives as anti-coagulants | SCHERING AG (DE) | 2001-01-31 | — | — | CN | claimed |
| CN-1221419-A | Amide derivatives | OTSUKA PHARMA CO LTD (JP) | 1999-06-30 | — | — | CN | claimed |
| EP-0888336-A1 | NOVEL SUBSTITUTED N-METHYL-N-(4-(4-(1H-BENZIMIDAZOL-2-YL-AMINO)P IPERIDIN-1-YL)-2-(ARYL)BUTYL)BENZAMIDES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | HOECHST MARION ROUSSEL, INC. (US) | 1999-01-07 | — | — | EP | claimed |
| WO-1997030989-A1 | NOVEL SUBSTITUTED N-METHYL-N-(4-(4-(1H-BENZIMIDAZOL-2-YL-AMINO)PIPERIDIN-1-YL)-2-(ARYL)BUTYL)BENZAMIDES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | HOECHST MARION ROUSSEL, INC. (US) | 1997-08-28 | — | — | WO | claimed |
| US-4304935-A | Production of 1-phenyl-3-cyanoureas | REXOLIN CHEMICALS AB (SE) | 1981-12-08 | — | — | US | claimed |