Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | ADH1B | P00325 | 1/20 | 0.43 |
| ▸ | ADH1C | P00326 | 1/20 | 0.43 |
| ▸ | ADH1A | P07327 | 1/20 | 0.43 |
| ▸ | ADH4 | P08319 | 1/20 | 0.43 |
| ▸ | ADH7 | P40394 | 1/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28202256 | 1.00 | OPRM1 (0.50) | OPRM1TSHRTHRBGPR84SPHK1 | |
| SCHEMBL11333881 | 1.00 | OPRM1 (0.50) | OPRM1TSHRTHRBGPR84SPHK1 | |
| SCHEMBL28291438 | 1.00 | OPRM1 (0.50) | OPRM1TSHRTHRBGPR84SPHK1 | |
| Ammonia Solution, Strong SCHEMBL6405192 | 0.97 | OPRM1 (0.48) | OPRM1TSHRTHRBGPR84SPHK1 | |
| SCHEMBL4800234 | 0.95 | OPRM1 (0.46) | OPRM1TSHRTHRBGPR84SPHK1 | |
| SCHEMBL31342802 | 0.92 | OPRM1 (0.44) | OPRM1TSHRTHRBGPR84SPHK1 | |
| SCHEMBL11496797 | 0.92 | OPRM1 (0.48) | OPRM1TSHRTHRBGPR84SPHK1 | |
| SCHEMBL11491167 | 0.89 | OPRM1 (0.46) | OPRM1TSHRTHRBGPR84SPHK1 | |
| SCHEMBL7090425 | 0.89 | OPRM1 (0.46) | OPRM1TSHRTHRBGPR84SPHK1 | |
| SCHEMBL9206614 | 0.89 | OPRM1 (0.46) | OPRM1TSHRTHRBGPR84SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923569-B1 | BUTYRIC ACID MATRIX METALLOPROTEINASE INHIBITORS | WARNER LAMBERT CO (US) | 2004-11-17 | — | — | EP | disclosed |
| US-6020366-A | Butyric acid matrix metalloproteinase inhibitors | WARNER-LAMBERT COMPANY (US) | 2000-02-01 | — | — | US | disclosed |