Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.54 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.45 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.45 |
| ▸ | CLK2 | P49760 | 1/20 | 0.45 |
| ▸ | GSK3A | P49840 | 1/20 | 0.45 |
| ▸ | CDK9 | P50750 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.45 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 12/20 | 0.44 |
| ▸ | CDK2 | P24941 | 12/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6609299 | 0.92 | GSK3B (0.56) | GSK3BCDK5LIMK1CLK2GSK3A | |
| Hydrochloric Acid SCHEMBL3607549 | 0.90 | GSK3B (0.55) | GSK3BCDK5LIMK1CLK2GSK3A | |
| SCHEMBL6616768 | 0.79 | GSK3B (0.45) | GSK3BCDK5LIMK1CLK2GSK3A | |
| SCHEMBL6659931 | 0.78 | GSK3B (0.46) | GSK3BCDK5LIMK1CLK2GSK3A | |
| SCHEMBL4554916 | 0.76 | GSK3B (0.49) | GSK3BCDK5LIMK1CLK2GSK3A | |
| SCHEMBL6611369 | 0.74 | CDK5 (0.72) | GSK3BCDK5LIMK1CLK2GSK3A | |
| SCHEMBL10270155 | 0.71 | CCNA2 (0.51) | GSK3BCDK5LIMK1CLK2GSK3A | |
| SCHEMBL6754731 | 0.70 | CDK2 (0.58) | GSK3BCDK5CDK9CCNA2CDK2 | |
| SCHEMBL10270734 | 0.69 | MAPT (0.45) | GSK3BCDK5LIMK1CLK2GSK3A | |
| SCHEMBL7753414 | 0.68 | GSK3B (0.69) | GSK3BCDK5GSK3ACCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1547574-A | Novel 2, 4-diaminothiazole derivatives | ŵ��Ų�ڿ˹�˾ | 2004-11-17 | — | — | CN | disclosed |
| US-20040210063-A1 | Novel 2,4-diaminothiazole derivatives | NOVO NORDISK A/S (DK) | 2004-10-21 | — | — | US | disclosed |
| EP-1417188-A1 | NOVEL 2,4-DIAMINOTHIAZOLE DERIVATIVES | Novo Nordisk A/S (DK) | 2004-05-12 | — | — | EP | disclosed |
| WO-2003011843-A1 | NOVEL 2,4-DIAMINOTHIAZOLE DERIVATIVES | NOVO NORDISK A/S (DK) | 2003-02-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040210063-A1 | Novel 2,4-diaminothiazole derivatives | GSK3B, GSK3A, GYS2 | GSK3B 1/4885CDK5 749/4885LIMK1 822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.